Title: Two-dimensional gel proteome reference map of INS-1E cells
Authors: D'Hertog, Wannes
Maris, Michael
Thorrez, Lieven
Waelkens, Etienne
Overbergh, Lut ×
Mathieu, Chantal #
Issue Date: Apr-2011
Publisher: WILEY-VCH Verlag
Series Title: Proteomics vol:11 issue:7 pages:1365-1369
Abstract: The insulin-producing INS-1E rat cell line is widely used as a model for studying β-cells. It is a well-characterized cell line, mainly used in diabetes research. We established a 2-DE reference map for INS-1E cells. Using MALDI-TOF/TOF-MS/MS, we identified 546 spots. These included various proteins with an important role in β-cell physiology and with known roles as crucial proteins for diabetes development. We believe that the availability of this reference map will enhance our knowledge of β-cell physiology.
ISSN: 1615-9853
Publication status: published
KU Leuven publication type: IT
Appears in Collections:ESAT - STADIUS, Stadius Centre for Dynamical Systems, Signal Processing and Data Analytics
Development and Regeneration, Campus Kulak Kortrijk
Clinical and Experimental Endocrinology
Molecular Virology and Gene Therapy
Laboratory of Phosphoproteomics (-)
Laboratory of Protein Phosphorylation and Proteomics
× corresponding author
# (joint) last author

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