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Title: 4,6-Dichloro-2-oxa-5-azabicyclo[2.2.2]oct-5-en-3-ones and their use in the synthesis of 1,6-dihydro-6-oxo-2-pyridine- and 6-oxo-2-piperidinecarboxylates
Authors: Dubois, KJ ×
Fannes, CC
Compernolle, Frans
Hoornaert, Georges #
Issue Date: Jan-1996
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:52 issue:7 pages:2591-2602
Abstract: 4,6-Dichloro-2-oxa-5-azabicyclo[2.2.2]oct-5-en-3-ones obtained from cycloaddition of 2H-1,4-oxazin-2-ones and alkene compounds, undergo lactone cleavage with alcohols to yield 1,4,5,6-tetrahydro-5-hydroxy-6-oxo-2-pyridnecarboxylates which can be dehydrated or reduced to a afford 1,6-dihydro-6-oxo-2-pyridine- or 6-oxo-2-pipcridinecarboxylates.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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