Title: Development of new amino(oxo)piperidinecarboxylate scaffolds and their evaluation as beta-turn mimics
Authors: Verbist, BMP
De Borggraeve, Wim ×
Toppet, Suzanne
Compernolle, Frans
Hoornaert, GJ #
Issue Date: Jan-2005
Publisher: Wiley-v c h verlag gmbh
Series Title: European journal of organic chemistry issue:14 pages:2941-2950
Abstract: In this paper a synthetic approach for functionalised bicyclic Amino(oxo)piperidinecarboxylate (APC) systems is presented. These systems can potentially be applied as cis-peptide bond containing beta-turn mimics. The scope and limitations of the synthetic method are discussed and the turn-inducing properties of a model compound are evaluated by means of molecular modelling and NMR analysis. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
ISSN: 1434-193X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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