Title: Synthesis of mesoionic[1,2,3]triazolo[5,1-d][1,2,5]triazepines
Authors: Savel'eva, EA ×
Rozin, YA
Kodess, MI
Van Meervelt, Luc
Dehaen, Wim
Morzherin, YY
Bakulev, VA #
Issue Date: Jan-2004
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:60 issue:25 pages:5367-5372
Abstract: Intramolecular cyclization of 1-amino-3-phenacyl-4-carbohydrazido-1,2,3-triazolium-5-olates has been shown to take place via selective interaction of the carbonyl group with the terminal amino function of the hydrazido group to form a 1,2,5-triazepine ring. Minor products, resulting from the interaction of the a-nitrogen atom of the hydrazido group with the carbonyl function, having a N-aminopyridazine structure were also detected and isolated. A general method for the synthesis of novel mesoionic 2-amino-7-aryl-4-oxo-2,4,5,8-tetrahydro[1,2,3]triazolo[5,1-d][1,2,5]triazepin-9-ium-3-olates was developed. (C) 2004 Elsevier Ltd. All rights reserved.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Biochemistry, Molecular and Structural Biology Section
Molecular Design and Synthesis
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science