Title: Aerobic vaginitis in pregnancy
Authors: Donders, Gilbert ×
Bellen, G
Rezeberga, D #
Issue Date: Sep-2011
Publisher: Blackwell Science
Series Title: BJOG vol:118 issue:10 pages:1163-70
Article number: 10.1111/j.1471-0528.2011.03020.x
Abstract: Please cite this paper as: Donders G, Bellen G, Rezeberga D. Aerobic vaginitis in pregnancy. BJOG 2011; DOI: 10.1111/j.1471-0528.2011.03020.x. Aerobic vaginitis (AV) is an alteration in vaginal bacterial flora that differs from bacterial vaginosis (BV). AV is characterised by an abnormal vaginal microflora accompanied by an increased localised inflammatory reaction and immune response, as opposed to the suppressed immune response that is characteristic of BV. Given the increased local production of interleukin (IL)-1, IL-6 and IL-8 associated with AV during pregnancy, not surprisingly AV is associated with an increased risk of preterm delivery, chorioamnionitis and funisitis of the fetus. There is no consensus on the optimal treatment for AV in pregnant or non-pregnant women, but a broader spectrum drug such as clindamycin is preferred above metronidazole to prevent infection-related preterm birth. The exact role of AV in pregnancy, the potential benefit of screening, and the use of newer local antibiotics, disinfectants, probiotics and immune modulators need further study.
ISSN: 1470-0328
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Basic Research in Gynaecology Section (-)
Medicine Teaching Programs
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science