Title: The impact of the learning curve on adhesion formation in a laparoscopic mouse model
Authors: Corona, Roberta ×
Verguts, Jasper
Binda, Maria
Molinas, Carlos Roger
Schonman, Ron
Koninckx PR, Philippe #
Issue Date: Jul-2011
Publisher: American Society for Reproductive Medicine
Series Title: Fertility and sterility vol:96 issue:1 pages:193-7
Abstract: OBJECTIVE: To evaluate the impact of surgeon training on adhesion formation in a laparoscopic mouse model. Laparoscopic surgery and bowel manipulation was demonstrated to enhance postoperative adhesion formation. DESIGN: Prospective randomized, controlled trial. SETTING: University laboratory research center. ANIMAL(S): 200 BALB/c and 200 Swiss female mice. INTERVENTION(S): Adhesions were induced by opposing bipolar lesions and 60 minutes of pneumoperitoneum. Each surgeon operated on 80 mice (40 Swiss and 40 BALB/c), the only variable thus being his/her increasing experience. Some surgeons were already experienced gynecologists, others were starting their training. MAIN OUTCOME MEASURE(S): End points were the duration of surgery while performing the lesions. The adhesion formation was scored quantitatively (proportion and total) and qualitatively (extent, type, and tenacity) after 7 days. RESULT(S): With training, duration of surgery and adhesion formation decreased exponentially for all surgeons, whether experienced or not. Experienced surgeons had initially a shorter duration of surgery, less adhesion formation, and less de novo adhesions than inexperienced surgeons. CONCLUSION(S): These data suggest that laparoscopic skills improve with training, leading to a decrease in the duration of surgery and formation of adhesions. Therefore completion of a standardized learning curve should be mandatory when initiating adhesion formation studies both in laboratory or clinical setting.
ISSN: 0015-0282
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Basic Research in Gynaecology Section (-)
Section Woman - Miscellaneous (-)
Abdominal Surgical Oncology
× corresponding author
# (joint) last author

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