Author:

Abstract:

In vivo and in vitro neural interfaces are currently designed to achieve stimulation and recording of neural networks for neuroscience research. The main aim of this research is to get fully understanding of the brain functions. There exist many challenges for the design of accurate electronic interfaces, mainly related to the increasing density of multi-electrode arrays and the growing interest for simultaneous stimulation and recording. In this paper we describe our design strategy for approaching precise, simultaneous stimulation and recording from a multi-electrode neural probe. We present three aspects to this problem: finite element modeling of the electric field distribution to study the mechanism of action of stimulation, design of an integrated circuit for multi-electrode neural recording, and design of a discrete circuit for stimulus artifact removal during simultaneous stimulation and recording. Combining these three approaches gives us a more comprehensive understanding of the neural mechanism in the brain.