Title: The Fontan circulation: who controls cardiac output?
Authors: Gewillig, Marc ×
Brown, Stephen C
Eyskens, Benedicte
Heying, Ruth
Ganame, Javier
Budts, Werner
Gerche, Andre La
Gorenflo, Matthias #
Issue Date: Mar-2010
Publisher: Elsevier Science
Series Title: Interactive Cardiovascular and Thoracic Surgery vol:10 issue:3 pages:428-433
Abstract: In a Fontan circuit the mechanisms involved in control of cardiac output at rest and during exercise differ significantly from normal. The classical model presumes an unlimited preload which is not available in the Fontan circuit. This review critically analyses the role of contractility, heart rate, and afterload and highlights the importance of pulmonary vascular resistance (PVR) in determining adequate preload and, therefore, cardiac output in these patients. A conceptual model of the determinants of cardiac output in Fontan patients is presented.
ISSN: 1569-9293
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pediatric Cardiology Section (-)
Cardiovascular Developmental Biology
× corresponding author
# (joint) last author

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