Title: Pericardial effusions in adolescent girls with anorexia nervosa: clinical course and risk factors
Authors: Docx, Martine K F ×
Gewillig, Marc
Simons, Annik
Vandenberghe, Philippe
Weyler, Joost
Ramet, Jose
Mertens, Luc #
Issue Date: May-2010
Publisher: Brunner/Mazel Publishers
Series Title: Eating Disorders vol:18 issue:3 pages:218-25
Abstract: The aim of this study was to evaluate cardiac, biochemical and endocrine differences between female adolescents with anorexia nervosa (AN) with and without pericardial effusions. We studied 128 female adolescents (9.8-17.7 years) with anorexia nervosa (AN) diagnosed according to DSM-IV (American Psychiatric Association, 1994) criteria. They all underwent an echocardiographic evaluation. In 29 patients (22.2 %) a pericardial effusion (ranging between >or= 0.35-2.5 cm) was noted. None of the patients were clinically symptomatic. After 3 months of refeeding, the effusions disappeared in 18/29 patients while in 7/29 patients a pericardial effusion > 0.3 cm persisted. Risk factors for development of effusions were a BMI <or= 13,5 kg/m(2), weight loss >or= 25% and IGF-1-level <or=100 ng/ml. Pericardial effusions are common in adolescent AN patients. They are mostly asymptomatic not requiring any intervention and spontaneously regress with refeeding. They are more common in the patients with the most significant weight loss.
ISSN: 1064-0266
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Section Child - Miscellaneous (-)
Pediatric Cardiology Section (-)
Faculty of Science - miscellaneous
Cardiovascular Imaging and Dynamics
Cardiovascular Developmental Biology
× corresponding author
# (joint) last author

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