Title: Failure of epicardial pacing leads in congenital heart disease: not uncommon and difficult to predict
Authors: Post, M C ×
Budts, Werner
Van De Bruaene, Alexander
Willems, Rik
Meyns, Bart
Rega, Filip
Gewillig, Marc #
Issue Date: Aug-2011
Publisher: Bohn Stafleu van Loghum BV
Series Title: Netherlands Heart Journal vol:19 issue:7-8 pages:331-335
Abstract: AIMS: We evaluate the incidence of epicardial lead failure and try to identify risk factors in patients with congenital heart disease. METHODS: All patients with a congenital heart defect and an epicardial pacing system, implanted within a timeframe of 25 years, were included in this study. Patients' medical records and lead data were reviewed. Lead failure was defined as the primary endpoint. RESULTS: In total 198 active epicardial leads (atrial 40, ventricular 158) were implanted in 93 patients (median age at implantation 4.4 years (range 0-58.6)). During a total follow-up of 1235 lead-years, 29 lead failures (14.6%, 4 atrial, 25 ventricular) were documented in 22 patients (23.7%). Lead failure occurred at a median time period of 4.8 years (range 1.2-24.1) after implantation. Five-year freedom of lead failure was 88%. The only independent predictor for lead failure was the age at implantation (HR 0.44; 95%CI 0.20-0.97, p = 0.04), other characteristics failed to predict lead failure. Sudden cardiac death occurred in four patients (4.3%), in one a lead failure was documented. CONCLUSION: A high incidence of epicardial lead failures is found in patients with congenital heart disease. Unfortunately, it is difficult to predict this potentially life-threatening complication.
ISSN: 1568-5888
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Section Child - Miscellaneous (-)
Cardiac Surgery
Pediatric Cardiology Section (-)
Cardiovascular Developmental Biology
× corresponding author
# (joint) last author

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