Genome wide analysis of the bovine mucin genes and their gastrointestinal transcription profile
Hoorens, Prisca R × Rinaldi, Manuela Goddeeris, Bruno Claerebout, Edwin Vercruysse, Jozef Geldhof, Peter #
BMC Genomics vol:12
Mucins are large glycoproteins implicated in protection of all mucosal surfaces. In humans and rodents, the mucin gene family has been well described and previous studies have investigated the distribution and function of mucins in the gastrointestinal (GI) tract. In contrast, little data is available on the mucin gene family in polygastric species, such as cattle. The aim of the current study was to identify all members of the bovine mucin family by genome mining and subsequently investigate the transcription pattern of these mucins in the GI tract.