International Journal of Computational Intelligence Research vol:6 issue:4 pages:731-734
Protein C is an anti-thrombotic, anti-inflammatory serine protease, that is encoded by PROC gene in humans. Functional activated protein C (APC) levels are regulated by the serine protease inhibitor family of proteins, including α1-antitrypsin and protein C inhibitor . Although this enzyme has been well characterized in humans and in bovine, the assessment of this enzyme has not been carried out in other mammals, which would pave way for the understanding of the evolution of this enzyme. In this study, an in silico characterization of protein C enzyme has been accomplished in Macaca fascicularis, a primate, to study the sequence and structural features and also to identify new members of this enzyme in M. fascicularis.