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Title: Facile one-pot synthesis of novel 6-monosubstituted 5,11-dihydroindolo[3,2-b]carbazoles and preparation of different derivatives
Authors: Gu, Ron ×
Hameurlaine, Ahmed
Dehaen, Wim #
Issue Date: Jan-2006
Publisher: Georg thieme verlag kg
Series Title: Synlett issue:10 pages:1535-1538
Abstract: The synthesis of novel 6-monosubstituted 5,1 1-dihydroindolo[3.2-b]carbazoles was accomplished by a three-stage one-pot procedure involving condensation of indole and an aldehyde affording 3,3'-bis(indolyl)methanes, followed by isomerization to the 2,3'-analogues and acid-catalyzed intramolecular reaction with triethyl orthoformate to give the corresponding 6-monosubstituted indolo[3.2-b]carbazoles in good overall yield. Different substitution patterns, such as N-alkylation, N-arylation, formylation and bromination, were successfully introduced, leading to the formation of novel substituted 5,11-dihydroindolo[3,2-b]carbazole derivatives.
ISSN: 0936-5214
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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