Title: A microwave-assisted diastereoselective multicomponent reaction to access dibenzo[c,e]azepinones: synthesis and biological evaluation
Authors: Mehta, Vaibhav P ×
Modha, Sachin G
Ruijter, Eelco
Van Hecke, Kristof
Van Meervelt, Luc
Pannecouque, Christophe
Balzarini, Jan
Orru, Romano V A
Van der Eycken, Erik #
Issue Date: Apr-2011
Publisher: American Chemical Society
Series Title: Journal of Organic Chemistry vol:76 issue:8 pages:2828-2839
Abstract: An unprecedented microwave-assisted multicomponent strategy has been elaborated for the fast, efficient, and diastereoselective generation of the dibenzo[c,e]azepinone scaffold. The generated compounds were evaluated for their bioactivity.
ISSN: 0022-3263
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
Molecular Design and Synthesis
Biochemistry, Molecular and Structural Biology Section
× corresponding author
# (joint) last author

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