Title: Differential proteomics in dequeened honeybee colonies reveals lower viral load in hemolymph of fertile worker bees
Authors: Cardoen, Dries ×
Ernst, Uli
Van Vaerenbergh, Matthias
Boerjan, Bart
de Graaf, Dirk C.
Wenseleers, Tom
Schoofs, Liliane
Verleyen, Peter #
Issue Date: 15-Jun-2011
Publisher: Public Library of Sciene
Series Title: PLoS One vol:6 issue:6 pages:7
Article number: e20043
Abstract: The eusocial societies of honeybees, where the queen is the only fertile female among tens of thousands sterile worker bees, have intrigued scientists for centuries. The proximate factors, which cause the inhibition of worker bee ovaries, remain largely unknown; as are the factors which cause the activation of worker ovaries upon the loss of queen and brood in the colony. In an attempt to reveal key players in the regulatory network, we made a proteomic comparison of hemolymph profiles of workers with completely activated ovaries vs. rudimentary ovaries. An unexpected finding of this study is the correlation between age matched worker sterility and the enrichment of Picorna-like virus proteins. Fertile workers, on the other hand, show the upregulation of potential components of the immune system. It remains to be investigated whether viral infections contribute to worker sterility directly or are the result of a weaker immune system of sterile workers.
ISSN: 1932-6203
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Ecology, Evolution and Biodiversity Conservation Section
Animal Physiology and Neurobiology Section - miscellaneous
× corresponding author
# (joint) last author

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