Title: Telaprevir is effective given every 8 or 12 hours with ribavirin and peginterferon alfa-2a or -2b to patients with chronic hepatitis C
Authors: Marcellin, Patrick ×
Forns, Xavier
Goeser, Tobias
Ferenci, Peter
Nevens, Frederik
Carosi, Giampiero
Drenth, Joost P
Serfaty, Lawrence
De Backer, Koen
Van Heeswijk, Rolf
Luo, Donghan
Picchio, Gaston
Beumont, Maria #
Issue Date: Feb-2011
Publisher: W.B. Saunders
Series Title: Gastroenterology vol:140 issue:2 pages:459-U159
Abstract: Recent studies have shown that 12 weeks of treatment with telaprevir, administered every 8 hours (q8h), combined with pegylated interferon (peginterferon) alfa-2a plus ribavirin significantly increased the rate of hepatitis C virus (HCV) eradication (sustained virologic response [SVR]) in patients infected with HCV genotype 1 compared with approved therapy. We investigated the efficacy, safety, tolerability, and pharmacokinetics of telaprevir given q8h or every 12 hours (q12 h) in combination with peginterferon alfa-2a or alfa-2b.
ISSN: 0016-5085
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hepatology
× corresponding author
# (joint) last author

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