Title: LC Assay for a HIV Tablet Containing Emtricitabine, Tenofovir Disoproxil Fumarate and Rilpivirine
Authors: Pendela, Murali
Weldu, Getu Kahsay
Van den Mooter, Guy
Baert, Lieven
Hoogmartens, Jos
Adams, Erwin # ×
Issue Date: Mar-2011
Publisher: Friedrich Vieweg & Sohn
Series Title: Chromatographia vol:73 issue:5-6 pages:439-445
Abstract: A liquid chromatographic method with UV detection was developed for the assay of a tablet for HIV (human immunodeficiency virus) treatment containing three active components, which are emtricitabine, tenofovir disoproxil fumarate and rilpivirine. A Hypersil BDS-C18 column was used as stationary phase and the assay was performed with gradient elution using mobile phases containing acetonitrile, 0.2 M potassium dihydrogen phosphate and water. Dimethyl sulfoxide-distilled water (1:1) was used as solvent for the active components. The method proved to be selective, linear, repeatable, sensitive and easy to perform.
ISSN: 0009-5893
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pharmaceutical Analysis
Drug Delivery and Disposition
× corresponding author
# (joint) last author

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