Title: Using reciprocal derivative chronopotentiometry as a technique to determine safe charge injection limits of electrodes used for neural stimulation
Authors: Musa, Silke
Prodanov, Dimiter
Loo, Josine
Eberle, Wolfgang
Bartic, Carmen
Nuttin, Bart
Borghs, Gustaaf #
Issue Date: Sep-2010
Publisher: IEEE
Host Document: Proceedings of the 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - EMBC pages:2943-2946
Series Title: IEEE EMBC
Conference: 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - EMBC location:Buenos Aires Argentina date:31-aug-2010
Abstract: We used reciprocal derivative chronopotentiometry (RDC) with platinum electrodes of 50 μm diameter in 0.15 M phosphate buffered saline solution to identify the various elec- trochemical processes occurring at the electrode during biphasic current pulsing. RDC allowed to determine the limits of water hydrolysis based on the specific (dt/dE)−E data representation employed in this technique resulting in curves similar to the voltammetric i−E response. Current stimulation was performed by either varying the pulse amplitude or pulse width. We found that the limits for H2 and O2 evolution for constant-amplitude pulses lied at 0.51 mC/cm2 and 0.67 mC/cm2, respectively, while for constant-width pulses they occurred at slightly lower values of 0.49 mC/cm2 and 0.61 mC/cm2, respectively. We could also extract values for the anodic and cathodic overvoltages associated with gas evolution. The cathodic overvoltage for H2 evolution was 1.43 V for both constant-amplitude and constant-width pulses, while the anodic overpotentials for O2 evolution were 2.45 V in the first and 2.24 V in the latter case. These values are clearly larger than the gas evolution limits generally found with steady- state voltammetry.
ISBN: 978-1-4244-4124-2
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Semiconductor Physics Section
Research Group Experimental Neurosurgery and Neuroanatomy
Solid State Physics and Magnetism Section
# (joint) last author

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