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Title: Giant liver hemangioma: the role of female sex hormones and treatment
Authors: van Malenstein, Hannah ×
Maleux, Geert
Monbaliu, Diethard
Verslype, Chris
Komuta, MIna
Roskams, Tania
Laleman, Wim
Cassiman, David
Fevery, Johan
Aerts, Raymond
Pirenne, Jacques
Nevens, Frederik #
Issue Date: May-2011
Publisher: Current Science
Series Title: European Journal of Gastroenterology & Hepatology vol:23 issue:5 pages:438-443
Abstract: Hepatic hemangiomas are the most common focal liver lesions and are especially prevalent in women. Giant hemangiomas are defined as hemangiomas of at least 4 cm in diameter and the majority remains stable in size over time. However, in some cases hemangiomas display growth and give rise to symptoms because of their space-occupying effect. Causes for the enlargement of the tumors are unknown, but a role of female sex hormones has been suggested. Therefore, hormone therapy should be avoided in patients who became symptomatic. In patients with important symptoms, disease control can be obtained by transcatheter arterial embolization. In selected patients, especially in case of Kasabach-Merritt syndrome, there is a good indication for liver transplantation.
ISSN: 0954-691X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiology
Hepatology
Laboratory of Abdominal Transplantation
Translational Cell & Tissue Research
Laboratory of Nephrology
× corresponding author
# (joint) last author

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