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Title: Cycloadducts of ethene with 2(1h)-pyrazinones and their conversion into 2,5-diazabicyclo[2.2.2]octane-3,6-diones
Authors: Loosen, Pk ×
Tutonda, Mg
Khorasani, Mf
Compernolle, Frans
Hoornaert, Georges #
Issue Date: Jan-1991
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:47 issue:44 pages:9259-9268
Abstract: Cycloaddition of variously substituted 2(1H)-pyrazinones with ethene and subsequent hydrolysis of the adducts 2 provides a general and efficient route to the title compounds 3. Compound 3m was used as a building block for a structural analogue of gliotoxin.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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