Genome-wide analysis of Ollier disease: Is it all in the genes?
Pansuriya, Twinkal C × Oosting, Jan Krenacs, Tibor Taminiau, Antonie H. M Verdegaal, Suzan H. M Sangiorgi, Luca Sciot, Raf Hogendoorn, Pancras C. W Szuhai, Karoly Bovee, Judith V. M. G #
Orphanet Journal of Rare Diseases vol:6 issue:1
Background: Ollier disease is a rare, non-hereditary disorder which is characterized by the presence of multiple enchondromas (ECs), benign cartilaginous neoplasms arising within the medulla of the bone, with an asymmetric distribution. The risk of malignant transformation towards central chondrosarcoma (CS) is increased up to 35%. The aetiology of Ollier disease is unknown.