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Title: Prospective, randomized comparison of epidural and combined spinal epidural analgesia during labor
Authors: Van De Velde, Marc ×
Mignolet, K
Vandermeersch, Eugene
Van Assche, Frans Andre #
Issue Date: Jan-1999
Series Title: Acta anaesthesiologica Belgica vol:50 issue:3 pages:129-36
Abstract: The analgesic efficacy and incidence of maternal, fetal and neonatal side-effects of combined spinal epidural (CSE) and epidural (EPI) analgesia, using a mixture of bupivacaine 0.125%, epinephrine (1.25 and sufentanil (0.75 for the relief of labor pain, were randomly and prospectively compared in 110 parturients. A 29 gauge Whitacre tip spinal needle was used to perforate the dura in CSE patients. Compared to EPI, CSE resulted in rapid (326 +/- 22 vs 766 +/- 79 sec, p < 0.05), excellent analgesia, using less bupivacaine (23.5 +/- 2.3 vs 33.9 +/- 2.9 mg, p < 0.05) and sufentanil (12.5 +/- 1.0 vs 16.5 +/- .7 micrograms, p < 0.05). A tendency to improved patient satisfaction in the CSE group was observed. The incidence of maternal or neonatal side effects was similar in both groups. No PDPH was observed. We conclude that CSE analgesia results in excellent pain relief during labor with immediate gratification as compared to epidural analgesia.
ISSN: 0001-5164
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Anesthesiology and Algology
Section Woman - Miscellaneous (-)
Faculty of Medicine - miscellaneous
× corresponding author
# (joint) last author

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