Title: Long-term outcome after treatment of isolated pulmonary valve stenosis
Authors: Voet, A ×
Rega, Filip
de Bruaene, A Van
Troost, Els
Gewillig, Marc
Van Damme, Stephan
Budts, Werner #
Issue Date: Apr-2012
Publisher: Elsevier/North-Holland Biomedical Press
Series Title: International Journal of Cardiology vol:156 issue:1 pages:11-15
Abstract: BACKGROUND: Few data are available on very long-term follow-up after treatment for isolated pulmonary valve stenosis (PVS), either surgically or by percutaneous balloon angioplasty (PBA). METHODS AND RESULTS: All patients with isolated PVS were selected from our database of congenital heart defects. Their records were reviewed systematically. We identified 79 surgically treated patients with a median follow-up of 22.5years (range 0-45years) and 139 PBA patients with median follow-up of 6.0years (range 0-21years). Echocardiographic and catheterization parameters indicate excellent results of both techniques in relieving the transpulmonary gradient. However, after initial surgery 20.3% of patients needed a cardiac re-intervention: 81% for severe pulmonary valve regurgitation, but none for residual pulmonary stenosis. After initial PBA a cardiac re-intervention was needed in 9.4% of patients. In 85% the indication was residual pulmonary stenosis, in none of them pulmonary regurgitation, although almost all patients developed a mild pulmonary regurgitation. Freedom of re-intervention after surgery was 98.4%, 93.5%, 87.7%, 70.9% and 55.7% at 5, 10, 20, 30 and 40years postoperatively. Freedom of re-intervention in the PBA group was 95.1%, 87.5% and 84.4% at 5, 10 and 20years post-procedure. CONCLUSIONS: Both surgery and PBA are safe and successful in relieving the acute transpulmonary gradient. Long-term results of surgery are worse than previously thought due to severe PR. After PBA re-interventions for residual stenosis are frequently needed and the incidence of mild PR is high. Very long-term results of PBA are still unknown.
ISSN: 0167-5273
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical Cardiac Surgery
Cardiovascular Developmental Biology
× corresponding author
# (joint) last author

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