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Title: Comparison of intramuscular buprenorphine and a buprenorphine/naloxone combination in the treatment of post-operative pain
Authors: Vanacker, Bernard ×
Vandermeersch, Eugene
Tomassen, J #
Issue Date: Jan-1986
Series Title: Current medical research and opinion vol:10 issue:2 pages:139-44
Abstract: The analgesic efficacy and tolerance of a single intramuscular injection of either buprenorphine (0.3 mg) or a buprenorphine (0.3 mg)/naloxone (0.2 mg) combination was compared in 70 patients suffering from moderate to severe pain after abdominal surgery. Patients in both treatment groups experienced good analgesia which was apparent within 10 minutes of administration and lasted for approximately 12 hours. The most frequently reported unwanted effects were drowsiness and/or sleepiness and nausea and/or vomiting which were of mild or moderate severity in most cases. No significant differences were seen between the two treatment groups with regard to the overall assessments of efficacy and tolerance.
ISSN: 0300-7995
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Anesthesiology and Algology
× corresponding author
# (joint) last author

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