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Title: Glossopharyngeal neuralgia triggered by non-noxious stimuli at multiple cephalic and extracephalic sites
Authors: ter Berg, J. W. M ×
Dupont, Patrick
Schoenen, J #
Issue Date: Nov-2009
Publisher: Universitetsforlaget
Series Title: Cephalalgia vol:29 issue:11 pages:1174-1179
Abstract: Glossopharyngeal neuralgia (GN) triggered by non-noxious stimuli at multiple cephalic and extracephalic sites with positron emission tomography (PET) evidence for involvement of the upper brainstem has never been reported. We present such a patient, a 73-year-old man who since the age of 50 had suffered from GN with a high recurrence rate and very severe unilateral, non-familial GN episodes with very easy trigger zones widely extending beyond the n IX territory. Extensive neuroimaging and neurophysiological tests detected no precise underlying cause. PET scan revealed activation in the upper brainstem on extracephalic triggers. Single-fibre electromyography data will be discussed. We hypothesize that deficient inhibition as seen in trigeminal nociceptive reflexes on the level of brainstem interneurons, a functional lesion in the primary somatosensory cortex-sensory thalamic nuclei circuit and the dorsal column-thalamic pathway both activated by light touch may in part be involved in the extracephalic triggering.
URI: 
ISSN: 0333-1024
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory for Cognitive Neurology
Research Group Experimental Neurology
× corresponding author
# (joint) last author

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