Title: Pharmacokinetics of propofol during continuous infusion for pediatric anesthesia
Authors: Vandermeersch, Eugene ×
Van Hemelrijck, Jan
Byttebier, G
Van Aken, H #
Issue Date: Jan-1989
Series Title: Acta anaesthesiologica Belgica vol:40 issue:3 pages:161-5
Abstract: The blood concentrations of propofol have been examined during anesthesia by continuous infusion of 12 mg/hg/hr. A bolus dose of 3 mg/kg body weight propofol was used to induce anesthesia. The mean concentrations at apparent steady state were in the range of 4.3 to 5.6 micrograms/ml during the infusion. The mean total body clearance, derived from the apparent steady state concentrations in the blood, was 0.0394 litres/kg/minute. The mean propofol blood concentration at awakening was found to be 2.3 micrograms/ml.
ISSN: 0001-5164
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Anesthesiology and Algology
× corresponding author
# (joint) last author

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