Title: A first approach to an action spectrum for 8-MOP phototumorigenesis in mice
Authors: Young, A R ×
Walker, S L
Garmyn, Maria #
Issue Date: Feb-1988
Series Title: Journal of Investigative Dermatology vol:90 issue:2 pages:175-8
Abstract: Groups of hairless albino mice were treated with 8-MOP and exposed to a fixed daily dose of UVR obtained from one of four different emission spectra. Each spectrum was obtained by filtering a xenon arc source with a different WG filter. The resultant spectra showed differences in their proportions of shorter UVA wavelengths. A decreased proportion of the shorter wave bands systematically increased the time to first tumor. These data suggest that the action spectrum for 8-MOP sensitized phototumorigenesis is similar to that of acute 8-MOP action spectra in mammalian skin, which usually show maximal activity in the 320-335 nm region.
ISSN: 0022-202X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Dermatology
× corresponding author
# (joint) last author

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