Title: Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4
Authors: Szpirer, C ×
Szpirer, J
Rivière, M
Swinnen, Johan
Vicini, E
Conti, M #
Issue Date: Jan-1995
Publisher: S. Karger
Series Title: Cytogenetics and Cell Genetics vol:69 issue:1-2 pages:11-4
Abstract: Through the use of somatic cell hybrids segregating either human or rat chromosomes, we determined the chromosome localizations of two genes encoding cAMP-specific phosphodiesterases (cAMP-PDEs). PDE4D, the gene encoding the cAMP-PDE isoform 3 (IVd), was assigned to human chromosome 5 and rat chromosome 2, and PDE4B, the gene encoding the cAMP-PDE isoform 4 (IVb), was assigned to human chromosome 1 and rat chromosome 5. These localizations extend the homology between rat chromosome 2 and human chromosome 5, on the one hand, and between rat chromosome 5 and human chromosome 1, on the other hand.
ISSN: 0301-0171
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical and Experimental Endocrinology
Laboratory of Lipid Metabolism and Cancer (+)
× corresponding author
# (joint) last author

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