Title: Marked elevation and cyclic variation of corticosteroid-binding globulin: an inherited abnormality?
Authors: Coolens, J L ×
Heyns, Walter #
Issue Date: Feb-1989
Series Title: Journal of Clinical Endocrinology and Metabolism vol:68 issue:2 pages:492-4
Abstract: Unexplained high serum corticosteroid-binding globulin (CBG) concentrations [mean values, 78.8 and 55.7 mg/L; normal women, 38.8 +/- 3.8 (+/- SD) mg/L] were found repeatedly in two apparently healthy sisters who were not pregnant or taking exogenous estrogens. One had substantial variations in serum CBG and sex hormone-binding globulin concentrations during the menstrual cycle, which paralleled the normal cyclic changes in serum estradiol. The other woman was postmenopausal and had a high serum CBG concentration despite of low serum estradiol levels. We conclude those women have an inherited abnormality in CBG production.
ISSN: 0021-972X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical and Experimental Endocrinology
× corresponding author
# (joint) last author

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