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Title: Cortisol-free transcortin: preparation and effect on mitogen-stimulated lymphocytes
Authors: Faict, D ×
De Moor, Pieter
Van Baelen, Hugo
Heyns, Walter
Stevens, Erik
Ceuppens, Jan #
Issue Date: Oct-1983
Series Title: Journal of steroid biochemistry vol:19 issue:4 pages:1397-401
Abstract: Human cortisol-free transcortin was prepared from charcoal-treated serum. The major purification was achieved by affinity chromatography on an immunoadsorbent column of transcortin antibodies coupled to Sepharose 4B. A further purification on hydroxylapatite yielded pure transcortin with preserved steroid-binding activity. This preparation had no significant influence on the proliferation of human lymphocytes stimulated with phytohemagglutinin, nor did it increase the inhibition of lymphocyte proliferation by cortisol or dexamethasone.
ISSN: 0960-0760
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical and Experimental Endocrinology
Laboratory of Clinical Immunology
× corresponding author
# (joint) last author

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