Bisphosphonates and fractures of the subtrochanteric or diaphyseal femur
Black, Dennis M × Kelly, Michael P Genant, Harry K Palermo, Lisa Eastell, Richard Bucci-Rechtweg, Christina Cauley, Jane Leung, Ping Chung Boonen, Steven Santora, Arthur de Papp, Anne Bauer, Douglas C Fracture Intervention Trial Steering Committee HORIZON Pivotal Fracture Trial Steering Committee #
New England Journal of Medicine vol:362 issue:19 pages:1761-71
A number of recent case reports and series have identified a subgroup of atypical fractures of the femoral shaft associated with bisphosphonate use. A population-based study did not support this association. Such a relationship has not been examined in randomized trials.