Title: Activation volumes for horseradish peroxidase compound II reactions
Authors: Ralston, I M ×
Wauters, J
Heremans, Karel
Dunford, H B #
Issue Date: Apr-1982
Series Title: Biophysical chemistry vol:15 issue:1 pages:15-8
Abstract: The activation volumes for the reactions of horseradish peroxidase compound II with L-tyrosine, 3-iodo-L-tyrosine, p-aminobenzoic acid and ferrocyanide were determined by using a high-pressure stopped-flow technique at 25 degrees C and pH 7. For the tyrosines, the solvent electrostriction accompanying substrate ionization and H+ transfer from the substituted phenol to a basic group of the enzyme can account for the observed negative activation volumes. For p-aminobenzoic acid a simple electron transfer without H+ transfer appears to occur. The positive activation volume for ferrocyanide may be explained in terms of electron transfer associated with a large change in electrostriction of the inorganic redox couple.
ISSN: 0301-4622
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Biochemistry, Molecular and Structural Biology Section
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science