DETC Induces Leishmania Parasite Killing in Human In Vitro and Murine In Vivo Models: A Promising Therapeutic Alternative in Leishmaniasis
Khouri, Ricardo Novais, Fernanda Santana, Giselia de Oliveira, Camila Indiani Vannier dos Santos, Marcos Andre Barral, Aldina Barral-Netto, Manoel Van Weyenbergh, Johan # ×
Public Library of Sciene
PLoS One vol:5 issue:12
Background: Chemotherapy remains the primary tool for treatment and control of human leishmaniasis. However, currently available drugs present serious problems regarding side-effects, variable efficacy, and cost. Affordable and less toxic drugs are urgently needed for leishmaniasis.