Title: Simultaneous maximum a posteriori reconstruction of attenuation and activity distributions from emission sinograms
Authors: Nuyts, Johan
Dupont, Patrick
Stroobants, S
Benninck, R
Mortelmans, Luc
Suetens, Paul #
Issue Date: May-1999
Series Title: IEEE transactions on medical imaging vol:18 issue:5 pages:393-403
Abstract: In order to perform attenuation correction in emission tomography an attenuation map is required. We propose a new method to compute this map directly from the emission sinogram, eliminating the transmission scan from the acquisition protocol. The problem is formulated as an optimization task where the objective function is a combination of the likelihood and an a priori probability. The latter uses a Gibbs prior distribution to encourage local smoothness and a multimodal distribution for the attenuation coefficients. Since the attenuation process is different in positron emission tomography (PET) and single photon emission tomography (SPECT), a separate algorithm for each case is derived. The method has been tested on mathematical phantoms and on a few clinical studies. For PET, good agreement was found between the images obtained with transmission measurements and those produced by the new algorithm in an abdominal study. For SPECT, promising simulation results have been obtained for nonhomogeneous attenuation due to the presence of the lungs.
ISSN: 0278-0062
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Nuclear Medicine & Molecular Imaging
ESAT - PSI, Processing Speech and Images
Research Group Experimental Neurology
Laboratory for Cognitive Neurology
# (joint) last author

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