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Title: Role of contrast agent perfusion and of diffusion in the NMR signal enhancement of liver lesions
Authors: Marchal, Guy
Ni, Yicheng
Van Damme, B
Van Damme, Boudewijn
Van Hecke, Paul
Michiels, J
Yu, Jie
Zhang, Xu
Baert, A L #
Issue Date: Oct-1992
Series Title: Journal of computer assisted tomography vol:16 issue:5 pages:690-8
Abstract: Both perfusion and diffusion contribute to NMR signal enhancement after intravenous injection of a nonspecific contrast agent. In the present study the roles of perfusion and diffusion in the contrast enhancement of induced liver lesions in the rat and the rabbit were evaluated. This was done by comparing Gd-DOTA absolute enhancement signal-to-noise versus time plots of various lesions with the findings from microangiography and histology. Four types of enhancement could be recognized. Diffusion was the major factor in the delayed enhancement seen in lesions that had large extravascular diffusion space.
ISSN: 0363-8715
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiology
Translational Cell & Tissue Research
Theragnostic Laboratory (+)
# (joint) last author

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