Title: Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients
Authors: Vanhorebeek, Ilse ×
Gunst, Jan
Derde, Sarah
Derese, Inge
Boussemaere, Magaly
Guiza Grandas, Fabian
Martinet, Wim
Timmermans, Jean-Pierre
D'Hoore, André
Wouters, Pieter
Van den Berghe, Greet #
Issue Date: Apr-2011
Publisher: Issued for the Endocrine Society by the Williams & Wilkins Co.
Series Title: Journal of Clinical Endocrinology & Metabolism vol:96 issue:4 pages:E633-E645
Abstract: Responses to critical illness, such as excessive inflammation and hyperglycemia, may trigger detrimental chain reactions that damage cellular proteins and organelles. Such responses to illness contribute to the risk of (nonresolving) multiple organ dysfunction and adverse outcome.
ISSN: 0021-972X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Unit for Clinical-Translational Research (-)
Laboratory for Intensive Care Medicine (-)
Abdominal Surgical Oncology
Laboratory of Intensive Care Medicine
× corresponding author
# (joint) last author

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