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Title: Association analysis of PPARGC1A mutations with meat quality parameters in a commercial hybrid pig population
Authors: Erkens, T ×
De Smet, S
Van den Maagdenberg, K
Stinckens, Anneleen
Buys, Nadine
Van Zeveren, A
Peelman, L. J #
Issue Date: May-2010
Publisher: Česká akademie zemědělských věd
Series Title: Czech Journal of Animal Science vol:55 issue:5 pages:200-208
Abstract: Peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) is a promising candidate gene for selection on meat and carcass quality traits in the pig industry. In the pig, several SNPs have been reported in both coding and regulatory regions of this gene, some of which were associated with fat characteristics, but none of these associations have been confirmed and many SNPs have not yet been evaluated. Therefore, 18 PPARGC1A SNPs were genotyped in 65 slaughter pigs of a commercial hybrid population and used in an association analysis with multiple muscle and carcass traits. Several SNPs located in the 3'UTR and exon 8 and 9 of PPARGC1A were significantly (P < 0.05-0.001) associated with various carcass composition, tenderness and muscle fibre traits. They could potentially serve as DNA selection markers, if their impact was to be confirmed by a functional analysis.
ISSN: 1212-1819
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Gene Technology (-)
× corresponding author
# (joint) last author

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