Title: Measuring appropriate use of antibiotics in pyelonephritis in Belgian hospitals
Authors: Camberlin, Cecile * ×
Ramaekers, Dirk * #
Issue Date: May-2009
Publisher: Elsevier Science Publishers
Series Title: Computer Methods and Programs in Biomedicine vol:94 issue:2 pages:143-151
Abstract: Inappropriate use of antibiotics can induce antibiotic resistance, treatment failure, increased costs and even mortality. We developed a methodology for measuring guideline compliance of hospital antibiotic prescriptions in community-acquired acute pyelonephritis in Belgium. The claims and clinical data of all Belgian hospitalizations for community-acquired acute pyelonephritis were extracted from a nationwide administrative database. In a clinically homogeneous subset of patients, the percentage of patients who received a guideline-compliant prescription was calculated according to prescription guidelines disseminated in Belgium. In the group of non-pregnant adult female patients, 31% of the prescriptions were not in strict compliance with the guideline. Interhospital variability ranged from 0% to 100% compliance. We conclude that administrative databases can be used to analyze antibiotic prescription behavior in hospitals for homogeneous and clinically relevant patient groups. The interhospital, variability observed in Belgian hospitals indicate that there is a clear room for improvement. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
ISSN: 0169-2607
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Faculty of Medicine - miscellaneous
Department of Public Health miscellaneous
* (joint) first author
× corresponding author
# (joint) last author

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