Archive of applied mechanics vol:80 issue:5 pages:513-525
The precise failure mechanisms of bone implants are still incompletely understood. Micro-computed tomography in combination with finite element analysis appears to be a potent methodology to determine the mechanical stability of bone-implant constructs. To assess this microstructural finite element (mu FE) analysis approach, pull-out tests were designed and conducted on ten sheep vertebral bodies into which orthopedic screws were inserted. mu FE models of the same bone-implant constructs were then built and solved, using a large-scale linear FE-solver. mu FE calculated pull-out strength correlated highly with the experimentally measured pull-out strength (r (2) = 0.87) thereby statistically supporting the mu FE approach. These results suggest that bone-implant constructs can be analyzed using mu FE in a detailed and unprecedented way. This could potentially facilitate the development of future implant designs leading to novel and improved fracture fixation methods.