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Title: The podocyte: from bench to bedside
Authors: Scharpe, J ×
Maes, Bart
Van Damme, Boudewijn #
Issue Date: Mar-2005
Series Title: Acta Clinica Belgica vol:60 issue:2 pages:86-93
Abstract: The understanding of the molecular structure of the podocyte has increased considerabely in recent 5 years by genetic research in inherited glomerulopathies. Injury to the podocyte often leads to a reorganisation of the slit diaphragm and to foot process effacement, which can be noted in all forms of the nephrotic syndrome. Since the recent progress in our understanding of the molecular biology of the podocyte, it has become obvious that the podocyte is crucial in the pathogenesis of not only genetic but also of many acquired glomerulopathies such as focal segmental glomerulosclerosis, membranous glomerulopathy and diabetic nephropathy. In this review we provide a summary of the recent physiological and molecular insights into the podocyte and of its significance in different glomerulopathies.
ISSN: 1784-3286
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
Laboratory of Nephrology
× corresponding author
# (joint) last author

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