Title: Food applications of bacterial cell wall hydrolases
Authors: Callewaert, Lien
Walmagh, Maarten
Michiels, Christiaan ×
Lavigne, Rob #
Issue Date: Apr-2011
Publisher: Current Biology
Series Title: Current Opinion in Biotechnology vol:22 issue:2 pages:164-171
Abstract: Bacterial cell wall hydrolases (BCWHs) display a remarkable structural and functional diversity that offers perspectives for novel food applications, reaching beyond those of the archetype BCWH and established biopreservative hen egg white lysozyme. Insights in BCWHs from bacteriophages to animals have provided concepts for tailoring BCWHs to target specific pathogens or spoilage bacteria, or, conversely, to expand their working range to Gram-negative bacteria. Genetically modified foods expressing BCWHs in situ showed successful, but face regulatory and ethical concerns. An interesting spin-off development is the use of cell wall binding domains of bacteriophage BCWHs for detection and removal of foodborne pathogens. Besides for improving food safety or stability, BCWHs may also find use as functional food ingredients with specific health effects.
ISSN: 0958-1669
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Gene Technology (-)
Centre for Food and Microbial Technology
× corresponding author
# (joint) last author

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