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Title: Two categories of synovial sarcoma defined by divergent chromosome translocation breakpoints in Xp11.2, with implications for the histologic sub-classification of synovial sarcoma
Authors: Renwick, P J ×
Reeves, B R
Dal Cin, Paola
Fletcher, C D
Kempski, H
Sciot, Raphael
Kazmierczak, B
Jani, K
Sonobe, H
Knight, J C #
Issue Date: Jan-1995
Publisher: S. Karger
Series Title: Cytogenetics and Cell Genetics vol:70 issue:1-2 pages:58-63
Abstract: Molecular analysis of a new series of synovial sarcomas confirms that t(X;18)(p11.2;q11.2) breakpoints occur at two distinct regions on Xp designated SS1 and SS2. Breakpoint position correlates with tumor phenotype. Monophasic tumors with no evidence of glandular components have breakpoints within the SS2 region in Xp11.21, and biphasic tumors with a focal poorly differentiated or extensive glandular structure have breakpoints within the SS1 region in Xp11.23.
ISSN: 0301-0171
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
Clinical Genetics Section (-)
× corresponding author
# (joint) last author

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