Title: Interstitial deletion 2p accompanied by marker chromosome formation of the deleted segment resulting in a stable acentric marker chromosome
Authors: Petit, P ×
Fryns, Jean-Pierre #
Issue Date: 1997
Series Title: Genetic counseling (Geneva, Switzerland) vol:8 issue:4 pages:341-3
Abstract: We reexamined a moderately mentally retarded patient with mild dysmorphism previously described with de novo 47,XY, del(2)(p11;p21), +acefr. Using fluorescence in situ hybridization (FISH), we now confirm the chromosome 2 nature of the extra marker resulting from interstitial deletion of del(2)(p11;p21) as well the lack alpha satellite DNA pattern. The authors suggest that a reactivation process of a latent centromere may explain the origin of this stable extra marker.
ISSN: 1015-8146
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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