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Title: Donor site morbidity after cartilage repair procedures: a review
Authors: Matricali, Giovanni ×
Dereymaeker, G.
Luyten, Frank #
Issue Date: Oct-2010
Publisher: Acta Medica Belgica
Series Title: Acta Orthopaedica Belgica vol:76 issue:5 pages:669-674
Abstract: In order to perform an Osteochondral Autologous
Transplantation (OAT) or an Autologous Chondrocyte
Implantation (ACI), the integrity of healthy intact
articular cartilage at a second location needs to be
violated . This creates the possibility for donor site
morbidity . Only recently have any publications
addressed this issue. The aim of this manuscript is to
review the current knowledge on donor site morbidity
after an OAT or an ACI.
Reports were identified by searching Medline and
Pubmed up to March 2010. Donor site morbidity was
described mostly considering a clinical outcome, both in
a qualitative (parameters in history or physical examination)
and/or quantitative way (knee status reported
by means of a numerical score). An increasing rate of
problems is noted when using quantitative instead of
qualitative parameters, and when donor site morbidity
is the focus of attention, affecting up to more than half
of the patients, in particular for an OAT procedure.
The decision to harvest an osteochondral or cartilage
biopsy to perform a repair procedure should therefore
be taken with caution. This also underscores the need
for further research to identify safe donor sites or to
develop techniques that eliminate the need for a formal
biopsy ccompletely.
ISSN: 0001-6462
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Orthopaedics Section (-)
Rheumatology Section (-)
× corresponding author
# (joint) last author

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