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Title: Embryonal rhabdomyosarcoma with only numerical chromosome changes. Case report and review of the literature
Authors: Polito, P ×
Dal Cin, Paola
Sciot, Raphael
Brock, P
Van Eyken, P
Van den Berghe, Herman #
Issue Date: Mar-1999
Publisher: Elsevier Science Pub. Co.
Series Title: Cancer Genetics and Cytogenetics vol:109 issue:2 pages:161-5
Abstract: An embryonal rhabdomyosarcoma, presenting as a retroperitoneal mass in a 15-year-old girl, is reported. The histological and immunohistochemical picture was typical, except for the presence of focal chondroid differentiation. Interestingly, expression of the "muscle markers" desmin and alpha-sarcomeric actin was present in the latter areas. Cytogenetic analysis showed a hyperdiploid karyotype without structural chromosome changes. The pertinent literature on the subject is reviewed. Hyperdiploidy of the clonal type seems to occur frequently, but no characteristic karyotype is so far emerging.
URI: 
ISSN: 0165-4608
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
Clinical Genetics Section (-)
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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