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Title: Long-term follow-up of 44 patients with adenocarcinoma of the nasal cavity and sinuses primarily treated with endoscopic resection followed by radiotherapy
Authors: Van Gerven, Laura
Jorissen, Mark
Nuyts, Sandra
Hermans, Robert
Vander Poorten, Vincent # ×
Issue Date: 21-Jun-2011
Publisher: J. Wiley
Series Title: Head & Neck vol:33 issue:6 pages:898-604
Abstract: BACKGROUND: Endoscopic resection followed by radiotherapy as primary treatment for adenocarcinoma of the sinuses is emerging as an alternative to open resection. METHODS: A total of 44 patients primarily treated by an endoscopic approach followed by radiotherapy from 1992 to 2004 seen at our ENT-Department were analyzed for outcome and prognostic factors. RESULTS: Median follow-up was 61 months. Median follow-up of the patients alive at the end of the follow-up period was 100 months. For the 5-year follow-up, the overall survival, disease-specific survival, and recurrence-free survival were 63% (±7% SE), 82% (±6), and 60% (±8%), respectively. The overall survival, disease-specific survival, and recurrence-free survival after 100 months of follow-up were 53% (±8%), 72% (±9%), and 54% (±9%), respectively. Four factors significantly influenced the disease-specific survival. CONCLUSION: This study of a homogeneous cohort of patients with sinonasal adenocarcinoma treated by endoscopic resection and radiotherapy confirms that endoscopic resection is a valid alternative to open resection. © 2010 Wiley Periodicals, Inc. Head Neck, 2010.
URI: 
ISSN: 1043-3074
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Experimental Oto-rhino-laryngology
Laboratory of Experimental Radiotherapy
Radiology
Head and Neck Oncology (+)
× corresponding author
# (joint) last author

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