Title: Capsazepine, a vanilloid receptor antagonist, inhibits allergen-induced tracheal contraction
Authors: van den Worm, Edwin
de Vries, Annick ×
Nijkamp, Frans P
Engels, Ferdi #
Issue Date: Jul-2005
Series Title: European journal of pharmacology vol:518 issue:1 pages:77-78
Abstract: To investigate the possible role of the vanilloid receptor-1 (TRPV1) in allergic airway responses, the effect of the specific TRPV1 receptor antagonist capsazepine was examined. Capsazepine significantly decreased the ovalbumin-induced contraction of isolated tracheal rings from ovalbumin-sensitized guinea pigs. This is the first report directly showing the involvement of the TRPV1 in experimental allergic airway responses.
ISSN: 0014-2999
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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