Title: Intravascular low-power red laser light as an adjunct to coronary stent implantation: initial clinical experience
Authors: De Scheerder, I K ×
Wang, K
Zhou, X R
Szilard, Monika
Verbeken, Eric
Ping, Q B
Yanming, H
Jianhua, H
Van de Warf, F #
Issue Date: Apr-2000
Series Title: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions vol:49 issue:4 pages:468-71
Abstract: Low-power red laser light (LPRLL) irradiation enhances endothelial cell growth in vitro and in vivo and reduces restenosis in animal models. The present study reports the preliminary clinical experience in our center. Eighty-one patients were treated with LPRLL, 30 mW/1 min, for in-stent restenosis (n = 27), elective stenting for recurrent restenosis (n = 16), and stenting for treatment of a suboptimal PTCA result (n = 38). All interventions were successful and no major adverse events due to LPRLL therapy were observed. At follow-up, 12 patients (14.8%) underwent an early control coronarogram due to target vessel restenosis. At 6 months, another 20 patients showed a significant restenosis of the target vessel. Preliminary clinical evaluation demonstrates that LPRLL is feasible and safe. The preliminary results suggest that LPRLL results in a decrease of in-stent restenosis when used during primary stenting.
ISSN: 1522-1946
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
× corresponding author
# (joint) last author

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