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Title: Immunohistochemical demonstration of lysozyme in pseudopyloric glands in chronic cholecystitis
Authors: van den Oord, Joost ×
Geboes, Karel
Peeters, C
Desmet, V J #
Issue Date: Jan-1983
Series Title: Virchows Archiv. A, Pathological anatomy and histopathology vol:399 issue:3 pages:317-23
Abstract: Gallbladders of 12 cases with chronic cholecystitis showing pseudopyloric glands (PPG) and of 18 cases with acute cholecystitis or chronic cholecystitis but without PPG were examined by the peroxidase - antiperoxidase (PAP) method using rabbit antibody against human lysozyme (LM). LM-immunoreactivity was detected in the cytoplasm of PPG and, to a lesser extent, in the pits of epithelial crypts that gave rise to PPG. No LM was found in normal gallbladders; in cases of cholecystitis without PPG, LM-immunoreactivity was restricted to infiltrating inflammatory cells. The presence of LM in PPG suggests that PPG represent functional metaplastic areas, involved in the non-specific defence mechanisms through participation of LM.
ISSN: 0174-7398
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
× corresponding author
# (joint) last author

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