Title: Rotavirus surveillance in Europe, 2005-2008: Web-enabled reporting and real-time analysis of genotyping and epidemiological data
Authors: Iturriza-Gomara, Miren ×
Dallman, T
Banyai, Krisztian
Bottiger, B
Buesa, Javier
Diedrich, Sabine
Fiore, L
Johansen, K
Korsun, N
Kroneman, Annelies
Lappalainen, M
Laszlo, B
Maunula, Leena
Matthijnssens, Jelle
Midgley, Sofie
Mladenova, Zornitsa
Poljsak-Prijatelj, Mateja
Pothier, Pierre
Ruggeri, Franco Maria
Sanchez-Fauquier, Alicia
Schreier, E
Steyer, A
Sidaraviciute, I
Tran, Anh Nhi
Usonis, Vytautas
Van Ranst, Marc
de Rougemont, A
Gray, James #
Issue Date: Nov-2009
Publisher: Published by the University of Chicago Press for the Infectious Diseases Society of America
Series Title: The Journal of Infectious Diseases vol:200 pages:S215-S221
Abstract: BACKGROUND: The first European rotavirus surveillance network, EuroRotaNet, comprising 16 laboratories in 15 European countries, has been established. METHODS: Fecal samples from gastroenteritis cases positive for group A rotavirus antigen were collected from multiple European countries from 2005 to mid-2008 and were subjected to G and P genotyping. Epidemiological data collected included age, sex, geographical location, setting, dates of onset and sample collection, and clinical symptoms. RESULTS: A total of 8879 rotavirus-positive samples were characterized: 2129 cases were from the 2005-2006 season, 4030 from the 2006-2007 season, and 2720 from the ongoing 2007-2008 season. A total of 30 different G and P type combinations of strains circulated in the region from 2005 through 2008. Of these strains, 90% had genotypes commonly associated with human infections-G1P[8], G2P[4], G3P[8], G4P[8], and G9P[8]-and 1.37% represented potential zoonotic introductions. G1P[8] remained the most prevalent genotype in Europe as a whole, but the incidence of infection with G1P[8] rotavirus strains was <50% overall, and all 3 seasons were characterized by a significant diversity of cocirculating strains. The peak incidence of rotavirus infection occurred from January through May, and 81% of case patients were aged <2.5 years. Conclusions. Data gathered through EuroRotaNet will provide valuable background information on the rotavirus strain diversity in Europe before the introduction of rotavirus vaccines, and the network will provide a robust method for surveillance during vaccine implementation.
ISSN: 0022-1899
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical and Epidemiological Virology (Rega Institute)
× corresponding author
# (joint) last author

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